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研究员，博士生导师；<\/span>1964年4月生于山东，中国国籍。<\/span><\/span>1984<\/span>年毕业于山东师范大学；<\/span><\/span>1989<\/span>年获法国艾克斯马赛大学博士学位。<\/span><\/span>1989-1991<\/span>于瑞士苏黎士大学从事博士后研究。<\/span><\/span>1991-1999<\/span>年任法国路易巴斯德大学讲师。<\/span><\/span>1999-2015<\/span>任法国艾克斯马赛大学教授。<\/span><\/span>2001-2006<\/span>年受聘为华中农业大学农业微生物国家重点实验室主任。曾任艾克斯马赛大学理学院院长及<\/span><\/span>Luminy<\/span>校区校长。<\/span><\/span>2015<\/span>年作为<\/span><\/span>QR<\/span>学者加入中国科学院⽔⽣生物研究所，并担任中国科学院藻类生物学重点实验室主任。<\/span>2024年起担任水生生物研究所藻类与生物制造研究中心主任。<\/span><\/span>在<\/span>PNAS(第一或通信作者8篇), Annual Review of Microbiology, Trends in Plant Science等杂志发表论文近百篇。<\/span><\/span>主持国家<\/span><\/span>科技部合成生物学重点专项<\/span>1项、国家自然科学基金重大研究计划2项；国家自然科学基金重点项目1项、国家自然科学基金重大计划项目1项、中国科学院前沿科学重点研究项目1项；作为课题负责人参与中科院先导<\/span><\/span>B<\/span>项目<\/span>1项。<\/span><\/span><\/p>

2015年至今已培养博士研究生7名，硕士研究生5名，出站博士后1名；引进中国科学院国际人才计划“特需人才计划”PIFI人才1名；培养中国科学院特聘研究骨干2名；培养湖北省青年拔尖人才1名；培养湖北省百人计划创新人才1名；培养武汉英才优秀青年2名；引进中国科学院择优支持“引才计划”B类人才1名（进行中）。<\/span><\/span><\/p>

目前在站培养博士后<\/span>4名，在读博士研究生7名，在读硕士研究生1名。<\/span><\/span><\/p>

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以蓝细菌为材料，从事原核生物细胞尺寸、发育、分裂等细胞形态形成相关的基础生物学研究，及蓝藻生物技术及水华蓝藻治理相关的合成生物学研究。在多年研究的基础上，在国际上首先建立了蓝藻碳氮代谢平衡的基本模型。首先发现蓝藻细胞分裂和细胞分化的联系，并以此开辟了新的研究领域。<\/span><\/span><\/p>

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国家杰青获得者；长江学者；法国教育部骑士勋章获得者；<\/span><\/span>留法校友会华中区杰出校友。<\/span><\/span><\/p><\/div>" var cdkyxmqk="

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  1. Su-Juan Liu, Gui-Ming Lin, Yu-Qi Yuan, Wenli Chen, Ju-Yuan Zhang and <\/span>Cheng-Cai Zhang<\/span><\/strong> (2024) A protein inhibitor brings under check the activity of RNase E in cyanobacteria. <\/span>Nucl. Acids Res<\/span><\/em><\/strong>. 52:404-419.<\/span><\/li>
  2. Jing Liu, Wei-Yue Xing, Bowen Liu, <\/span>Cheng-Cai Zhang <\/span><\/strong>(2023) Three-dimensional coordination of cell-division site positioning in a filamentous cyanobacterium. <\/span>PNAS Nexus<\/span><\/em><\/strong> 2(2) :<\/span>p<\/span><\/span>gac307.<\/span><\/li>
  3. Xiaoli Zeng, Min Huang, Qing-Xue Sun, Ye-Jun Peng, Xiaomei Xu, Yun-Bin Tang, Ju-Yuan Zhang, Yiling Yang, <\/span>Cheng-Cai Zhang<\/span><\/strong> (2023) A c-di-GMP binding effector controls cell size in a cyanobacterium. <\/span>Proc Natl Acad Sci USA<\/span><\/em><\/strong>, 120 :<\/span>e<\/span><\/span>2221874120.<\/span><\/li>
  4. Xiaoli Zeng and <\/span>Cheng-Cai Zhang <\/span><\/strong>(2022) The making of a heterocyst in cyanobacteria. <\/span>Ann Rev Microbiol<\/span><\/em><\/strong>. 76: 597-618. 48. <\/span><\/li>
  5. Wei-Yue Xing, Jing Liu, Ju-Yuan Zhang, Xiaoli Zeng, and <\/span>Cheng-Cai Zhang<\/span><\/strong> (2022) A proteolytic pathway coordinates cell division and heterocyst differentiation in the cyanobacterium Anabaena sp. PCC 7120. <\/span>Proc Natl Acad Sci USA<\/span><\/em><\/strong>, 119:e2207963119.<\/span><\/li>
  6. Wei-Yue Xing, Jing Liu, Zi-Qian Wang, Ju-Yuan Zhang, Xiaoli Zeng, Yiling Yang and <\/span>Cheng-Cai Zhang<\/span><\/strong> (2021) HetF protein is a new divisome component in a filamentous and developmental cyanobacterium. <\/span>mBio<\/span><\/em><\/strong>. 12:e01382-21.<\/span><\/li>
  7. Yong-Liang Jiang, Xue-Ping Wang, Hui Sun, Shu-Jing Han, Wei-Fang Li, Ning Cui, Gui-Ming Lin, Ju-Yuan Zhang, Wang Cheng, Dong-Dong Cao, Zhi-Yong Zhang, <\/span>Cheng-Cai Zhang<\/span><\/strong>, Yuxing Chen, Cong-Zhao Zhou (2018) Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR. <\/span>Proc Natl Acad Sci USA<\/span><\/em><\/strong>. 115:403-408. <\/span><\/li>
  8. Cheng-Cai Zhang<\/span><\/strong>, Cong-Zhao Zhou, Robert L. Burnap, Ling Peng (2018) Carbon\/Nitrogen Metabolic Balance: Lessons from Cyanobacteria.<\/span> <\/span>Trends in Plant Sci<\/span><\/em><\/strong>. 23:1116-1130.<\/span><\/li>
  9. Zhao, Meng.-Xi., et al., Chen, Yuxing, <\/span>Cheng-Cai Zhang<\/span><\/strong>,<\/span> <\/span>and Cong-zhao Zhou. (2010) Structural basis for the allosteric control of the global nitrogen-regulating transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. *Co-corresponding authors. <\/span>Proc Natl Acad Sci USA<\/span><\/em><\/strong>.<\/span> <\/span>107 :12487-12492.<\/span><\/li>
  10. Cheng-Cai Zhang<\/span><\/strong> and Cong-Zhao Zhou (2013) ATPase as a switch in PII signal transduction.<\/span> Proc Natl Acad Sci USA<\/span><\/em><\/strong> 110:12863-12864.<\/span><\/li>
  11. Amel Latifi, Marion Ruiz, and <\/span>Cheng-Cai Zhang<\/span><\/strong> (2009) Oxidative stress in cyanobacteria. <\/span>FEMS Microbiol. Rev<\/span><\/em><\/strong>., 33:258-278.<\/span><\/li>
  12. Sophie Laurent, Han Chen, Sylvie Bédu, Fabio Ziarelli, Ling Peng, and<\/span> Cheng-Cai Zhang,<\/span><\/strong> (2005) Nonmetabolizable analogue of 2-oxoglutarate elicits heterocyst differentiation under repressive conditions in Anabaena sp. strain PCC 7120. <\/span>Proc Natl Acad Sci USA<\/span><\/em><\/strong>.<\/span> <\/span><\/em><\/strong>102:9907-9912.<\/span><\/li>
  13. Cheng-Cai Zhang<\/span><\/strong> (1993) A gene encoding a protein related to eukaryotic-type protein kinases from the filamentous heterocystous cyanobacterium Anabaena PCC 7120. <\/span>Proc Natl Acad Sci USA<\/span><\/em><\/strong>. 90: 11840-11844.<\/span><\/li>
  14. <\/span><\/span><\/li><\/ol>

     <\/p><\/div>" var dh="86-27-68780989" var shrz="2007-2019年为美国微水生物学会（ASM）杂志J. Bacteriol. 编委；2008-2014年任英国皇家微生物学协会期刊Microbiology执行编辑；2008年至今任美国微生物学协会期刊Journal of Bacteriology编委，并于2015被选为top-performing reviewer members之一；2012年至今为国务院侨办海外专家委员会委员；2008， 2011年分别担任欧洲EURESCO蓝藻生物能学会议副主席，主席；2020年至今担任美国微生物学会（American Society for Microbiology）会员；2022年Annual Review of Microbiology 特邀编辑，并从2023年开始任该杂志编辑；2022年起担任mLife副主编；2021年起至今任国际光合原核生物大学科技委员会成员，2022年在利物浦举行的第十七届国际光合原核生物大学上，为中国争得了第十八届会议的举办权（ISPP2025 青岛），作为相关领域最大的国际学术会议，将是第一次在中国召开；2023年起至今任洪山实验室固定研究人员；2024年起成为中国微生物学会永久会员；2024年3月起担任中国海洋湖沼学会藻类学分会常务委员；2024年8月起担任中国微生物学会自养微生物专业委员会主任。" var grwy="" var xb="男" $("#EXPERT_XM").text(xm); $("#EXPERT_XB").text(xb); $("#EXPERT_ZC").text(zc); $("#EXPERT_XL").text(xl); $("#EXPERT_DH").text(dh); $("#EXPERT_DZYJ").text(dzyj); $("#EXPERT_JL").html(jl); $("#EXPERT_YJFX").html(yjfx); $("#EXPERT_ZW").html(zw); $("#EXPERT_SHRZ").html(shrz); $("#EXPERT_HJJRY").html(hjjry); $("#EXPERT_DBLZ").html(dblz); $("#EXPERT_PIC").attr("src", pic); $("title").text(xm)

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