| 论文标题： | |
|---|---|
| 作者： | |
| 出版刊物： | |
| 出版日期： | |
| 出版年份： | |
| 卷/期： | |
| DOI： | |
| 论文摘要： | The ricefield eel (Monopterus albus), a protogynous hermaphrodite, is an important aquaculture freshwater fish in China. Intensive studies have focused on the sex reversal of this species, but the underlying mechanisms remain elusive. We performed comparative transcriptome analysis for gonadal tissues of female, intersex, and male ricefield eels. The results suggest that temperature may play a role in inducing the sex reversal. Moreover, an epithelial-mesenchymal transition (EMT) gene signature was found, suggesting an involvement of germinal epithelium in contributing to gonadal transformation. Our in vitro and in vivo experiments show that thermal cues are sensed by thermosensors such as Trpv4 in the gonadal cells of ricefield eels, which can be transduced to the sex determination cascades. The epithelial cells of germinal epithelium can become Sertoli cells via an EMT. Our study provides new insights into the molecular mechanisms underlying the sex reversal of ricefield eels. |
以下内容与「星空体育彩票最新版下载」同属公开资讯，可按栏目接着查阅相关条目。
本站按公开材料组织页面。需要原文时请核对应栏目发布页。
若从搜索引擎进入，可先确认当前栏目名称，再按需打开相关阅读。
