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| 论文摘要： | This study investigated the effects of dietary supplementation with the probiotic Bacillus pumilus on coho salmon (Oncorhynchus kisutch). A total of 360 juvenile fish, with an average initial weight of 130.75 f 1.33 g, were randomly assigned to four treatment groups, each with three replicates of 30 fish. The fish were then fed for 70 days using formulated diets containing four concentrations of B. pumilus: 0 (control group), 2 x 106, 4 x 108, and 8 x 1010 CFU/g. We then evaluated growth, nutrient metabolism, immune-related serum biochemical markers, enzyme activity, gene expression, and muscle composition. Additionally, we assessed intestinal histology and microbiota composition. Our findings revealed that B. pumilus significantly improved growth, protein and fat metabolism, and immune function compared to the control group. It also had a positive effect on the structure and function of the intestinal microbiota. The group receiving 4 x 108 CFU/g showed the greatest improvements. Overall, B. pumilus appears to be a promising probiotic for enhancing the health and performance of coho salmon in aquaculture. |
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