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论文摘要: This data descriptor presents a multi-omics resource for Crassostrea gigas and Crassostrea angulata, comprising genomic variants and transcriptomic profiles relevant to fatty acid metabolism traits. A 458-individual F2 hybrid population genotyped with a 100 K SNP array identified 344 SNPs and 742 candidate genes linked to C18:3 omega 3, EPA, and DHA variation. KEGG analysis highlighted 24 key genes, with 23 validated via GS-assisted GWAS, dominant genotype screening, and wild population resequencing. Differential expression analysis revealed 458 DEGs (266 between high/low EPA + DHA groups; 192 between species), overlapping with 152 genes from GWAS and selective sweeps. This integrated dataset provides foundational genetic references for studying omega-3 fatty acid dynamics, enabling future investigations into sustainable marine resource utilization and climate resilience.

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